N-Piperidinoethanol → 1-{2-[4-(3-Phenyl-1,4-benzoxathiin-2-yl)phenoxy]ethyl}piperidine

HRID 1696692Notes

Reaction equation

HRID 1696692 reaction equation
[C:1]1([C:7]2[S:12][C:11]3[CH:13]=[CH:14][CH:15]=[CH:16][C:10]=3[O:9][C:8]=2[C:17]2[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:24]1([CH2:30][CH2:31]O)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[C:1]1([C:7]2[S:12][C:11]3[CH:13]=[CH:14][CH:15]=[CH:16][C:10]=3[O:9][C:8]=2[C:17]2[CH:18]=[CH:19][C:20]([O:23][CH2:31][CH2:30][N:24]3[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]3)=[CH:21][CH:22]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 18232N-PiperidinoethanolHCID 593967364-(3-Phenyl-1,4-benzoxathiin-2-yl)phenol

Product 1

HCID 593967591-{2-[4-(3-Phenyl-1,4-benzoxathiin-2-yl)phenoxy]ethyl}piperidine

Procedure

The entitled compound was obtained according to the method of Example 3 but using 4-(3-phenyl-1,4-benzoxathiin-2-yl)phenol synthesized in Reference Example 1-1 and 2-piperidin-1-ylethanol as the starting material.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-51c9df87d79b4685894e8ba7224f479a
Source dataset
uspto-grants-2012_04
Patent number
US08163770B2

Reaction notes

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