HCID 59004213, compound → HCID 59004214, compound

Participants

Reaction Steps

To a solution of (4-Methoxy-2-nitro-phenyl)-(6-nitro-pyridin-3-yl)-amine (1.5 g, 1.55 mmol) in ethanol (50 ml) was added Pd/C (0.05 g) under N2. The mixture was shaken under a positive pressure of hydrogen at 5° C. for 4 h. After removal of the catalyst by filtration, the filtrate was concentrated by evaporation under vacuum using a rotary evaporator. The crude product, N5-(2-Amino-4-methoxy-phenyl)-pyridine-2,5-diamine, thus obtained was used directly for the next step.

Provenance & Evidence