m-Chloroperbenzoic acid → HCID 86630933, compound

Participants

Reaction Steps

To a solution of 0.282 g 2,6-dibromo-4-methylsulfanyl-pyridine (Example 45a) in 5.0 ml dichlormethane was added 0.246 g m-chloroperbenzoic acid at 0° C. and the mixture was then stirred at room temperature for 3 h. The reaction mixture was partitioned between 10% potassium carbonate and ethyl acetate. The phases were separated and the organic phase was washed with brine, dried over sodium sulphate and purified by chromatography on silica gel with ethyl acetate to yield 0.260 g of the title compound as white crystals melting at 98-100° C.

Provenance & Evidence