Ammonia → HCID 67274107, compound

HRID 1696786Notes

Reaction equation

HRID 1696786 reaction equation
C[O:2][C:3]([C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[C:7]([NH2:13])[N:6]=1)=O.[NH3:14]>>[NH2:13][C:7]1[N:6]=[C:5]([C:3]([NH2:14])=[O:2])[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 42609145Methyl 6-amino-4-methoxypyridine-2-carboxylate

Product 1

HCID 67274107HCID 67274107, compound

Procedure

In analogy to example 103b, by replacing 2,6-diaminoisonicotinic acid ethyl ester with 6-amino-4-methoxy-pyridine-2-carboxylic acid methyl ester and using 25% aqueous ammonia instead of methylamine, the title compound was obtained as white solid. MS (ISP) M+H+=168.4

Sources & evidence

ORD record
ord-7fea3b9fc8754445bc401d627efe86e2
Source dataset
uspto-grants-2012_04
Patent number
US08163778B2

Reaction notes

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