HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 66618240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 66618216 | HCID 66618216 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66618240 | HCID 66618240 | 96% |
Reaction Steps
To a cooled solution of (S)-3-[(4-fluoro-phenyl)-methyl-carbamoyl]-piperidine-1-carboxylic acid tert-butyl ester (0.205 g, 0.61 mmol) in dichloromethane (4 mL) was added dropwise 3 mL of HCl 4N (dioxane solution) and the solution was stirred at R.T. for 1 h. The solvent was evaporated under reduced pressure to give the title compound as a white solid (0.16 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163775B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-2057c6aa6f6c4c489f55c6da691fef9a |
| Source note | uspto-grants-2012_04 |