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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1696819Generated: November 1, 2026

Hydrochloric Acid → HCID 66618240, compound

https://huagongshe.com/reaction/1696819

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 66618216HCID 66618216—
SolventDichloromethaneHCID 6344—
ProductHCID 66618240HCID 6661824096%

Reaction Steps

To a cooled solution of (S)-3-[(4-fluoro-phenyl)-methyl-carbamoyl]-piperidine-1-carboxylic acid tert-butyl ester (0.205 g, 0.61 mmol) in dichloromethane (4 mL) was added dropwise 3 mL of HCl 4N (dioxane solution) and the solution was stirred at R.T. for 1 h. The solvent was evaporated under reduced pressure to give the title compound as a white solid (0.16 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163775B2
Source datasetuspto-grants-2012_04
ORD IDord-2057c6aa6f6c4c489f55c6da691fef9a
Source noteuspto-grants-2012_04