Methanol → HCID 66860779, compound

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A mixture of {4-[4-(4-{2-[3-(benzylmethanesulfonylamino)-4-benzyloxyphenyl]-2-(R)-hydroxyethylamino}butyl)phenyl]butyl}carbamic acid benzyl ester (36) (0.41 g, 0.54 mmol), palladium dihydroxide (0.12 g, 10% Pd(OH)2 on carbon, 50% wet), ten drops of acetic acid, methanol (9 mL), and dichloromethane (6 mL) was stirred at rt for 16 h under atmospheric hydrogen pressure. The catalyst was removed by filtration through a Celite pad and the filtrate was concentrated by rotary evaporation and further dried under high vacuum to give the desired amine diacetic acid salt 39 as a white solid (0.30 g, 96%): m/z (ESI) 450 [C23H35N3O4S+H]+.

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