4-Chlorophenol → HCID 59192594, compound

Participants

Reaction Steps

Starting with {(R)-5-[(3-chloro-4-fluoro-benzenesulfonyl)-methyl-amino]-5,6,7,8-tetrahydro-naphthalen-1-yloxy}-acetic acid tert-butyl ester (100 mg, 0.207 mmol) and 4-chlorophenol (315 mg, 2.45 mmol), using the method analogous to the one described for example 2-2, method D, 2nd step, ((R)-5-{[3-chloro-4-(4-chlorophenoxy)-benzenesulfonyl]-methyl-amino}-5,6,7,8-tetrahydro-naphthalen-1-yloxy)-acetic acid tert-butyl ester (92 mg, 75%) was obtained as a white powder. MS cald. For C29H31Cl2NO6S 591, obsd. 592 (ESI+) [(M+H)+].

Provenance & Evidence