HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azetidine → HCID 67275150, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azetidine | HCID 10422 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 86590508 | HCID 86590508 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67275150 | HCID 67275150 | — |
Reaction Steps
A mixture of ethyl 7-chloro-1-(2,4-dimethoxybenzyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate (254 mg), azetidine (0.085 mL), and potassium carbonate (160 mg) in dichloromethane (5 mL) was stirred for 3 days, diluted with dichloromethane, washed with water and 10% citric acid, filtered through a cotton plug, and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163769B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f66abe8c8583498f8612a2f759de1486 |
| Source note | uspto-grants-2012_04 |