Triethylamine → HCID 67275409, compound

Participants

Reaction Steps

A suspension of EXAMPLE 75B (350 mg) and triethylamine (0.098 mL) in dichloromethane (4 mL) and THF (3 mL) at 0° C. was treated with isopropenyl chloroformate (0.077 mL), stirred for 30 minutes, treated with concentrated ammonium hydroxide (0.100 mL), stirred for 18 hours at ambient temperature, loaded onto a flash silica gel column, and eluted with a methanol/dichloromethane gradient.

Provenance & Evidence