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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1697027Generated: November 2, 2026

2-Isocyanatothiophene → HCID 67019340, compound

https://huagongshe.com/reaction/1697027

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-IsocyanatothiopheneHCID 2776375—
ReactantHCID 86622654HCID 86622654—
ProductHCID 67019340HCID 67019340—

Reaction Steps

This compound is prepared analogously to N-{(1S,2R,3S,4R)-4-[2-{(R)-3-[3-(2,6-dichloro-pyridin-4-yl)-ureido]-pyrrolidin-1-yl}-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide trifluoroacetate (Example 73) by replacing 2,6-dichloro-4-isocyanato-pyridine with 2-thienyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163754B2
Source datasetuspto-grants-2012_04
ORD IDord-54196b0fb8d849529794b199e2de8e91
Source noteuspto-grants-2012_04