Acetone → HCID 59846291, compound

Participants

Reaction Steps

A mixture of 4-[(E)-3-(4-chloro-2-phenylamino-phenyl)-3-oxo-propenyl]-N-(4-hydroxy-cyclohexyl)-benzamide (197 mg) and platinum (V) oxide (50 mg) in a mixture of EtOH, THF and acetone (100/50/100 mL) was stirred under H2 (balloon pressure) at RT for 1 h. The resulting mixture was filtered, and the filtrate concentrate under reduced pressure to yield 4-[3-(4-chloro-2-phenylamino-phenyl)-3-oxo-propyl]-N-(4-hydroxy-cyclohexyl)-benzamide (190 mg).

Provenance & Evidence