Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Tritylamine | HCID 138598 | — |
| Reactant | Dibenzylphosphite | HCID 21904359 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 59534118 | HCID 59534118 | — |
Reaction Steps
A mixture of 1.00 g tritylamin in 20 ml of toluene is combined with 127 mg paraformaldehyde and 50 μl acetic acid and stirred for one hour at 80° C. Then 0.85 ml dibenzylphosphite are added and the reaction mixture is refluxed for three hours. Then 200 μl triethylamine are added and the reaction mixture is evaporated down in vacuo using the rotary evaporator. The flask residue is chromatographed through a silica gel column.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08163911B2 |
|---|
| Source dataset | uspto-grants-2012_04 |
|---|
| ORD ID | ord-10fa8566ce474eb6be960992d3b308cc |
|---|
| Source note | uspto-grants-2012_04 |
|---|
