HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 43448999, compound → Ethyl 3-amino-5-fluoro-4-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 43448999 | HCID 43448999 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 3-amino-5-fluoro-4-methylbenzoate | HCID 52982956 | 96.7% |
Reaction Steps
3-Fluoro-4-methyl-5-nitro-benzoic acid, ethyl ester (Example 169a, 1.43 g) in ethanol (30 mL) was pumped continuously through a Pd/C cartridge for 4 h under an atmosphere of hydrogen. The solvents were removed to give the subtitle product (1.20 g) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163905B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-6cb1d98a513a44a2aa2389135917fa85 |
| Source note | uspto-grants-2012_04 |