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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1697507Generated: November 1, 2026

P-Toluic Acid → HCID 46946817, compound

https://huagongshe.com/reaction/1697507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-Toluic AcidHCID 7470—
ReactantHCID 86646815HCID 86646815—
ProductHCID 46946817HCID 46946817—

Reaction Steps

(2S,4R)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide hydrochloride from experiment K2 was coupled with 4-methyl-benzoic acid in analogy to experiment A1 to give (2S,4R)-1-(4-methyl-benzoyl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide as a colorless oil. MS: 480.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163793B2
Source datasetuspto-grants-2012_04
ORD IDord-39bbaef44390402bb634e922b767f1d5
Source noteuspto-grants-2012_04