HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxane-4-carboxylic acid → HCID 46947014, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxane-4-carboxylic acid | HCID 219302 | — |
| Reactant | HCID 86646815 | HCID 86646815 | — |
| Product | HCID 46947014 | HCID 46947014 | — |
Reaction Steps
(2S,4R)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide hydrochloride from experiment K2 was coupled with tetrahydro-pyran-4-carboxylic acid in analogy to experiment A1 to give (2S,4R)-1-(tetrahydro-pyran-4-carbonyl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide as a colorless oil. MS: 474.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163793B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-bb974cbba0e54577bec585d3bd2e929b |
| Source note | uspto-grants-2012_04 |