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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1697532Generated: November 1, 2026

Formaldehyde → HCID 46947413, compound

https://huagongshe.com/reaction/1697532

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantHCID 66770259HCID 66770259—
ProductHCID 46947413HCID 46947413—

Reaction Steps

(2S,4R)-4-(2-chloro-benzenesulfonyl)-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide hydrochloride from experiment K4 was reductively alkylated with aqueous formaldehyde in analogy to experiment L3 to give (2S,4R)-4-(2-chloro-benzenesulfonyl)-1-methyl-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide as a colorless oil. MS: 368.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163793B2
Source datasetuspto-grants-2012_04
ORD IDord-c85785ccdbfc4aa68b66de9ec53461d8
Source noteuspto-grants-2012_04