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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1697587Generated: October 31, 2026

Lithium Hydroxide → HCID 66770790, compound

https://huagongshe.com/reaction/1697587

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 66771086HCID 66771086—
ProductHCID 66770790HCID 66770790—

Reaction Steps

In analogy to the procedure described in example 253e, (2S,4R)-1-[5-methyl-2-(2-methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester was saponified in the presence of lithium hydroxide to give the title compound as yellow solid. MS (ESI): m/z=495.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163793B2
Source datasetuspto-grants-2012_04
ORD IDord-93d547ff96ea4b20b0ffe3f58fe8e0d6
Source noteuspto-grants-2012_04