Lithium Hydroxide → HCID 66770432, compound

Participants

Reaction Steps

In analogy to the procedure described in example 253e, (2S,4R)-1-(2-tert-butyl-5-methyl-2H-pyrazol-3-yl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester was saponified in the presence of lithium hydroxide to give the title compound as yellow solid which was used in the next step without further purification. MS (ESI): m/z=458.1 [M−H]−.

Provenance & Evidence