HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydrazinylquinoline--hydrogen chloride (1/1) → HCID 66770803, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydrazinylquinoline--hydrogen chloride (1/1) | HCID 17750639 | — |
| Reactant | (2S,4R)-1-(3-oxo-thiobutyryl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester | HCID 86646823 | — |
| Product | HCID 66770803 | HCID 66770803 | — |
Reaction Steps
In analogy to the procedure described in example 192 h, (2S,4R)-1-(3-oxo-thiobutyryl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester (example 192 g) was reacted with quinolin-4-yl-hydrazine hydrochloride (CAS Reg. No. 68500-41-4) to give the title compound as orange oil. MS (ESI): m/z=545.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163793B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-2a2d7aeb60fd42f092059c2594c77d5e |
| Source note | uspto-grants-2012_04 |