Formaldehyde → HCID 66770566, compound

HRID 1697640Notes

Reaction equation

HRID 1697640 reaction equation
[CH2:1]([O:3][C:4](=[O:13])[CH2:5][NH:6][CH:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1)[CH3:2].[CH2:14]=O.[CH:16]([S:18]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[C:27]([F:30])([F:29])[F:28])(=[O:20])=[O:19])=[CH2:17]>>[CH2:1]([O:3][C:4]([CH:5]1[CH2:14][CH:16]([S:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[C:27]([F:28])([F:30])[F:29])(=[O:19])=[O:20])[CH2:17][N:6]1[CH:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1)=[O:13])[CH3:2]

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 234667181-Ethenesulfonyl-2-trifluoromethyl-benzeneHCID 43610081HCID 43610081, compound

Product 1

HCID 66770566HCID 66770566, compound

Procedure

In analogy to the procedure described in example 343d, (tetrahydro-pyran-4-ylamino)-acetic acid ethyl ester (CAS Reg. No. 1153226-50-6) was reacted with paraformaldehyde and 1-ethenesulfonyl-2-trifluoromethyl-benzene (example 243c) to give the title compound.

Sources & evidence

ORD record
ord-98168ad36f894c34992bd61597b5b9b2
Source dataset
uspto-grants-2012_04
Patent number
US08163793B2

Reaction notes

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