HRID1697672

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID17773358

(Oxan-4-yl)hydrazine--hydrogen chloride (1/1)

C5H13ClN2O

结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2C(F)(F)F)CN1C(=S)CC(C)=O

HCID86646829

未命名化合物

PRODUCTS

生成物

结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2C(F)(F)F)CN1c1cc(C)nn1C1CCOCC1

HCID67278636

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 192 h, (2S,4R)-4-(4-fluoro-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic acid methyl ester (example 388 d) was reacted with (tetrahydro-pyran-4-yl)-hydrazine hydrochloride (CAS Reg. No. 116312-69-7) to give the title compound as brown solid. MS (ESI): m/z=520.3 [M+H]+.