huagongshe.com
HRID1697674

反应详情

EQUATION

反应方程式

HRID 1697674 的结构方程式

REACTANTS

反应物

2
结构：Cl.NNC1CCC1
HCID19432792

Cyclobutylhydrazine--hydrogen chloride (1/1)

C4H11ClN2

结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1C(=S)CC(=O)C1CCOCC1
HCID86646857

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C2CCOCC2)nn1C1CCC1
HCID67278244

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 192 h, (2S,4R)-1-[3-oxo-3-(tetrahydro-pyran-4-yl)-thiopropionyl]-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester (example 393d) was reacted with cyclobutylhydrazine hydrochloride (CAS Reg. No. 158001-21-9) to give the title compound as yellow oil. MS (ESI): m/z=542.4 [M+H]+.