Formaldehyde → HCID 66771234, compound

HRID 1697685Notes

Reaction equation

HRID 1697685 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[CH2:5][NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:8]=1)[CH3:2].[CH2:18]=O.[CH:20]([S:22]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[C:31]([F:34])([F:33])[F:32])(=[O:24])=[O:23])=[CH2:21]>>[CH2:1]([O:3][C:4]([CH:5]1[CH2:18][CH:20]([S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31]([F:32])([F:34])[F:33])(=[O:23])=[O:24])[CH2:21][N:6]1[C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:8]=1)=[O:17])[CH3:2]

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 234667181-Ethenesulfonyl-2-trifluoromethyl-benzeneHCID 66770541HCID 66770541, compound

Product 1

HCID 66771234HCID 66771234, compound

Procedure

In analogy to the procedure described in example 343d, (3-methanesulfonyl-phenylamino)-acetic acid ethyl ester was reacted with paraformaldehyde and 1-ethenesulfonyl-2-trifluoromethyl-benzene (example 243c) to give the title compound as yellow oil. MS (ESI): m/z=506.1 [M+H]+.

Sources & evidence

ORD record
ord-05876e87ff974f4a82520519e9937ba6
Source dataset
uspto-grants-2012_04
Patent number
US08163793B2

Reaction notes

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