HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lawesson's reagent → HCID 67278578, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | Cyclobutylhydrazine--hydrogen chloride (1/1) | HCID 19432792 | — |
| Reactant | HCID 86646861 | HCID 86646861 | — |
| Product | HCID 67278578 | HCID 67278578 | — |
Reaction Steps
In analogy to the procedure described in example 308d, (2S,4R)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic acid methyl ester was reacted with Lawesson's reagent (CAS Reg. No. 19172-47-5) and cyclobutylhydrazine hydrochloride (CAS Reg. No. 158001-21-9) to give the title compound as brown oil. MS (ESI): m/z=549.8 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163793B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-78667ddc80f44f79aea6e9fe57d7e4fa |
| Source note | uspto-grants-2012_04 |