Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lawesson's reagent → (2S,4R)-4-Cyclopropylmethanesulfonyl-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic Acid Methyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lawesson's reagent | HCID 87949 | — |
| 반응물 | (2S,4R)-4-cyclopropylmethanesulfonyl-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic Acid Methyl Ester | HCID 86646863 | — |
| 생성물 | (2S,4R)-4-Cyclopropylmethanesulfonyl-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic Acid Methyl Ester | HCID 86646864 | — |
반응 단계
In analogy to the procedure described in example 192 g, (2S,4R)-4-cyclopropylmethanesulfonyl-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic acid methyl ester was reacted with Lawesson's reagent to give the title compound as brown solid. MS (ESI): m/z=348.4 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08163793B2 |
| 출처 데이터셋 | uspto-grants-2012_04 |
| ORD ID | ord-261e8dc7cb36434abced7eae42703190 |
| 출처 메모 | uspto-grants-2012_04 |