Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lawesson's reagent → (2S,4R)-Methyl 4-(2-chloro-4-fluorophenylsulfonyl)-1-(3-oxobutanethioyl)pyrrolidine-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lawesson's reagent | HCID 87949 | — |
| 반응물 | (2S,4R)-methyl 4-(2-chloro-4-fluorophenylsulfonyl)-1-(3-oxobutanoyl)pyrrolidine-2-carboxylate | HCID 86646855 | — |
| 생성물 | (2S,4R)-Methyl 4-(2-chloro-4-fluorophenylsulfonyl)-1-(3-oxobutanethioyl)pyrrolidine-2-carboxylate | HCID 86646870 | — |
반응 단계
In analogy to the procedure described in example 192 g, (2S,4R)-methyl 4-(2-chloro-4-fluorophenylsulfonyl)-1-(3-oxobutanoyl)pyrrolidine-2-carboxylate (example 375b) was reacted with Lawesson's reagent (CAS Reg. No. 19172-47-5) to give the title compound as orange foam. MS (ESI): m/z=421.9 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08163793B2 |
| 출처 데이터셋 | uspto-grants-2012_04 |
| ORD ID | ord-319b8940e86d49c6abd50edc7a54e6e5 |
| 출처 메모 | uspto-grants-2012_04 |