3-phenylpropylhydrazine → HCID 66771931, compound

HRID 1697763Notes

Reaction equation

HRID 1697763 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([C@H:11]1[CH2:15][N:14]([C:16](=S)[CH2:17][C:18](=O)[CH3:19])[C@H:13]([C:22]([O:24][CH3:25])=[O:23])[CH2:12]1)(=[O:10])=[O:9].[C:26]1([CH2:32][CH2:33][CH2:34][NH:35][NH2:36])[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[CH3:25][O:24][C:22]([C@@H:13]1[CH2:12][C@@H:11]([S:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])(=[O:9])=[O:10])[CH2:15][N:14]1[C:16]1[N:35]([CH2:34][CH2:33][CH2:32][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:36]=[C:18]([CH3:19])[CH:17]=1)=[O:23]

Participants

3

Reactant 2

HCID 188093-phenylpropylhydrazineHCID 86646820(2S,4R)-methyl 4-(2-chlorophenylsulfonyl)-1-(3-oxobutanethioyl)pyrrolidine-2-carboxylate

Product 1

HCID 66771931HCID 66771931, compound

Procedure

In analogy to the procedure described in example 192 h, (2S,4R)-methyl 4-(2-chlorophenylsulfonyl)-1-(3-oxobutanethioyl)pyrrolidine-2-carboxylate (example 253c) was reacted with 1-(3-phenylpropyl)hydrazine (CAS Reg. No. 3381-02-0) to give the title compound as yellow oil. MS (ESI): m/z=502.1 [M+H]+.

Sources & evidence

ORD record
ord-99e4ade38a42475babe80e51809ba505
Source dataset
uspto-grants-2012_04
Patent number
US08163793B2

Reaction notes

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