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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1697764Generated: October 31, 2026

Lithium Hydroxide → HCID 66771990, compound

https://huagongshe.com/reaction/1697764

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 66771931HCID 66771931—
ProductHCID 66771990HCID 66771990—

Reaction Steps

In analogy to the procedure described in example 253e, (2S,4R)-4-(2-chlorophenylsulfonyl)-1-(3-methyl-1-(3-phenylpropyl)-1H-pyrazol-5-yl)pyrrolidine-2-carboxylic acid methyl ester was saponified in the presence of lithium hydroxide to give the title compound as colorless oil which was used in the next step without further purification. MS (ESI): m/z=486.2 [M−H]−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163793B2
Source datasetuspto-grants-2012_04
ORD IDord-2afe780f77ea4a9d835a6ac3756d3531
Source noteuspto-grants-2012_04