Isopropyl chloroformate → (S)-isopropyl 2-(4-(3-ethylureido)phenyl)-4-(3-methylmorpholino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

Participants

Role	Name	HCID	Charge
Reactant	Isopropyl chloroformate	HCID 7917	—
Reactant	(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)urea	HCID 46913569	—
Product	(S)-isopropyl 2-(4-(3-ethylureido)phenyl)-4-(3-methylmorpholino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate	HCID 59239557	—

Reaction Steps

Compound et was prepared according to the procedure described in Example 5 by reacting (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)urea with isopropyl chloroformate. LC-MS: m/z=+483 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08163763B2
Source dataset	uspto-grants-2012_04
ORD ID	ord-f8d0927190394132b7e4b6b29aee379e
Source note	uspto-grants-2012_04