2-(2-Methoxyethoxy)acetyl chloride → (S)-1-ethyl-3-(4-(6-(2-(2-methoxyethoxy)acetyl)-4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)urea

Participants

Role	Name	HCID	Charge
Reactant	2-(2-Methoxyethoxy)acetyl chloride	HCID 7010338	—
Reactant	(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)urea	HCID 46913569	—
Product	(S)-1-ethyl-3-(4-(6-(2-(2-methoxyethoxy)acetyl)-4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)urea	HCID 59239251	—

Reaction Steps

Compound ez was prepared according to the procedure described in Example 5 by reacting (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)urea with 2-(2-methoxyethoxy)acetyl chloride. LC-MS: m/z=+513 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08163763B2
Source dataset	uspto-grants-2012_04
ORD ID	ord-d7c0b6d0c0be4bfa8d3e31eed300447e
Source note	uspto-grants-2012_04