1-Methylcyclopropanecarboxylic acid → HCID 59239563, compound

HRID 1697926Notes

Reaction equation

HRID 1697926 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:14]=[C:15]([N:23]3[CH2:28][CH2:27][O:26][CH2:25][CH2:24]3)[C:16]3[CH2:22][CH2:21][NH:20][CH2:19][C:17]=3[N:18]=2)=[CH:9][CH:8]=1)=[O:5])[CH3:2].[CH3:29][C:30]1([C:33](O)=[O:34])[CH2:32][CH2:31]1>>[CH2:1]([NH:3][C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]([C:13]2[N:14]=[C:15]([N:23]3[CH2:24][CH2:25][O:26][CH2:27][CH2:28]3)[C:16]3[CH2:22][CH2:21][N:20]([C:33]([C:30]4([CH3:29])[CH2:32][CH2:31]4)=[O:34])[CH2:19][C:17]=3[N:18]=2)=[CH:11][CH:12]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 813261-Methylcyclopropanecarboxylic acidHCID 469130711-Ethyl-3-(4-(4-morpholino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl) phenyl)urea

Product 1

HCID 59239563HCID 59239563, compound

Procedure

Compound fd was prepared according to the procedure described in Example 213 by reacting 1-ethyl-3-(4-(4-morpholino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea with 1-methylcyclopropanecarboxylic acid. LC-MS: m/z=+465 (M+H)+.

Workup

  1. customCompound fd was prepared

Sources & evidence

ORD record
ord-18f2e0f826034178aa1e015de2d3c032
Source dataset
uspto-grants-2012_04
Patent number
US08163763B2

Reaction notes

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