Dimethylformamide → HCID 44816805, compound

Participants

Reaction Steps

Step 3—Synthesis of compound ug: 5-(4-morpholino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)-1H-benzo[d]imidazol-2(3H)-one (0.297 g, 0.843 mmol), 2-Chloropyrimidine (0.145 g, 1.27 mmol), N,N-Dimethylformamide (10.0 mL, 129 mmol) and N,N-Diisopropylethylamine (0.588 mL, 3.38 mmol) were combined. The reaction solution was microwaved on 300 watts, 120° C. for 30 minutes on a CEM microwave. The reaction solution was filtered and washed with dichloromethane. LC/MS-m/z+431.2 (M+H)+

Provenance & Evidence