HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (S)-1-(5-methanesulfonyl-furan-2-yl)-propylamine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | (R)-2-methyl-propane-2-sulfinic acid [(S)-1-(5-methanesulfonyl-furan-2-yl)-propyl]amide | HCID 59278508 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (S)-1-(5-methanesulfonyl-furan-2-yl)-propylamine hydrochloride | HCID 66727537 | — |
Reaction Steps
To a solution of (R)-2-methyl-propane-2-sulfinic acid [(S)-1-(5-methanesulfonyl-furan-2-yl)-propyl]amide (0.530 g, 1.72 mmol) in methanol (5 mL) was added 4 N HCl in dioxane (2 mL, 8 mmol). After 1 hour, the mixture was concentrated in vacuo to afford (S)-1-(5-methanesulfonyl-furan-2-yl)-propylamine hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163918B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-df0379d96b0f4442aca616e80b0610da |
| Source note | uspto-grants-2012_04 |