Ammonium → Tert-butyl cis-4-amino-3-ethoxy-piperidine-1-carboxylate

HRID 169830Notes

Reaction equation

HRID 169830 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][CH:9]1[CH:10]([O:22][CH2:23][CH3:24])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1.[CH3:29][OH:30].[CH:25]([O-:26])=[O:27].[NH4+:28]>>[NH2:8][CH:9]1[CH:10]([O:22][CH2:23][CH3:24])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1

Participants

5

Reactant 4

HCID 223AmmoniumHCID 283FormateHCID 887MethanolHCID 68418201Tert-butyl 4-(benzylamino)-3-ethoxypiperidine-1-carboxylate

Product 1

HCID 68416085Tert-butyl cis-4-amino-3-ethoxy-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-56208a4540de4302a5624bafc9addedf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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