HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl isocyanate → HCID 57870321, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl isocyanate | HCID 76639 | — |
| Reactant | HCID 131729670 | HCID 131729670 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 57870321 | HCID 57870321 | — |
Reaction Steps
The title compound is prepared analogously as described in Example 98 using (3R*,5S*)-3-amino-5-{cyclopropyl-[3-(3-methoxy-propoxy)-4-methyl-benzyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester, hydrochloride (Example 98A.) and benzylisocyanate. MS: 509.6 [M+H]+; tR (HPLC, Nucleosil C18; 5-100% CH3CN+0.1% TFA/H2O+0.1% TFA for 8 min, flow 1.5 ml/min): 5.22 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163773B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-a11a8e56fe554714be58f700fe64bc46 |
| Source note | uspto-grants-2012_04 |