HCID 67273353, compound → HCID 57870318, compound

Participants

Reaction Steps

The title compound is prepared by Fmoc deprotection of (3R,5S)-3-{Cyclopropyl-[4-(3-methoxy-propyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl]-carbamoyl}-5-(2-hydroxymethyl-3-methyl-butyrylamino)-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester analogously as described in Example 134. MS: 545 [M+H]+; tR (HPLC, ACQUITY UPLC™ BEH C18 1.7 μm, 50×2.1 mm; 5% CH3CN+0.1% TFA/H2O+0.1% TFA for 0.5 min then 5-100% CH3CN+0.1% TFA/H2O+0.1% TFA for 5 min then 100% CH3CN+0.1% TFA for 1.5 min, flow 0.5 ml/min): 2.43, 2.61 min.

Provenance & Evidence