反应详情

A suspension of piperidine-1,3,5-tricarboxylic acid 1-tert-butyl ester (1 g, 3.6 mmol) in acetic anhydride (20 mL) is heated at reflux for 2 h. The reaction mixture is evaporated 3× times with toluene before it is dried under high vacuum at rt overnight to give a yellow solid. MS (LC-MS): 278 [M+Na]+.

1. temperatureis heated
2. temperatureat reflux for 2 h
3. customThe reaction mixture is evaporated 3× times with toluene before it
4. customis dried under high vacuum at rt overnight
5. customto give a yellow solid