HCID 86646565, compound → HCID 86646564, compound

Participants

Reaction Steps

In a manner analogous to example 1 e, the process is carried out by a reaction of 800 mg (3 mmol) of 3-tert-butyl-4-(ethylisobutylamino)benzaldehyde with 8 ml (4 mmol) of a 0.5M solution of ethynylmagnesium bromide. 700 mg of 1-[3-tert-butyl-4-(ethylisobutyl-amino)phenyl]prop-2-yn-1-ol are obtained in the form of a colourless oil (yield=81%).

Provenance & Evidence