反应详情

In a manner analogous to example 1 e, the process is carried out by a reaction of 1 g (4.9 mmol) of 3-tert-butyl-4-dimethylaminobenzaldehyde with 12 ml (6 mmol) of a 0.5M solution of ethynylmagnesium bromide. 900 mg of 1-(3-tert-butyl-4-dimethylaminophenyl)prop-2-yn-1-ol are obtained in the form of a colourless oil (yield=79%).