Dimethylformamide → HCID 86646569, compound

Participants

Reaction Steps

In a manner analogous to example 1 d, the process is carried out by a reaction of 9.9 g (34 mmol) of 1-(4-bromo-2-tert-butylphenyl)piperidine with 20 ml (50 mmol) of a 2.5M solution of n-butyllithium and 3.9 ml (50 mmol) of DMF. 8.8 g of 3-tert-butyl-4-piperidin-1-ylbenzaldehyde are obtained in the form of a yellow oil (yield=100%).

Provenance & Evidence