2-Isopropylaniline → 4-Bromo-2-(propan-2-yl)aniline

HRID 1698420노트

반응식

HRID 1698420 반응식
[Br-:1].[Br-].[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C([N+](CCCC)(CCCC)CCCC)CCC.C([N+](CCCC)(CCCC)CCCC)CCC.[CH:55]([C:58]1[CH:64]=[CH:63][CH:62]=[CH:61][C:59]=1[NH2:60])([CH3:57])[CH3:56]>>[Br:1][C:63]1[CH:62]=[CH:61][C:59]([NH2:60])=[C:58]([CH:55]([CH3:57])[CH3:56])[CH:64]=1

참가 물질

3

반응물 2

HCID 125612-IsopropylanilineHCID 23500184Tetra-n-butylammonium tribromide

생성물 1

HCID 222719374-Bromo-2-(propan-2-yl)aniline수율 57%

실험 절차

In a manner analogous to example 9a, the process is carried out by a reaction of 89 g (185 mmol) of tetra-n-butylammonium tribromide with 25 g (185 mmol) of 2-isopropylaniline. 22 g of 4-bromo-2-isopropyl-phenylamine are obtained (yield=57%).

출처 및 근거

ORD 기록
ord-e7e8117bfa8643838cfdf43a13d5e134
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08163952B2

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