HCID 57959828, compound → HCID 57959912, compound

Participants

Reaction Steps

{1-[4-(Propylsulphonyl)phenyl]-2-pyrrolidin-1-ylethyl}amine, the intermediate described in Example 47e, was reacted with 2-cyclopropylquinoline-4-carbonyl chloride (see above) under the conditions described in Example 47f. 1H NMR δ (400 MHz, CDCl3) δ 0.97 (3H, t, J=7.4 Hz), 1.07-1.11 (2H, m), 1.16-1.20 (2H, m), 1.66-1.77 (6H, m), 2.18-2.24 (1H, m), 2.48-2.50 (2H, m), 2.63-2.71 (3H, m), 2.91-3.02 (3H, m), 5.19-5.24 (1H, m), 7.29 (1H, s), 7.42-7.48 (2H, m), 7.56 (2H, d, J=8.3 Hz), 7.62-7.66 (1H, m), 7.82 (2H, d, J=8.3 Hz), 7.96 (1H, d, J=8.4 Hz), 8.13 (1H, d, J=8.3 Hz); m/z (ES+) 492 (M+H).

Provenance & Evidence