HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1698517Generated: October 30, 2026
Thionyl Chloride → 2-Methoxy-4-methyl-6-(trifluoromethyl)-3-pyridinecarbonyl chloride
https://huagongshe.com/reaction/1698517
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 67275887 | HCID 67275887 | — |
| Product | 2-Methoxy-4-methyl-6-(trifluoromethyl)-3-pyridinecarbonyl chloride | HCID 57959894 | — |
Reaction Steps
Thionyl chloride (2 mL) was added to 2-methoxy-4-methyl-6-(trifluoromethyl)-nicotinic acid (68 mg, 0.29 mmol) and then the mixture was heated at 60° C. for 1 hour. The mixture was evaporated to dryness.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08163956B2 |
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| Source dataset | uspto-grants-2012_04 |
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| ORD ID | ord-bc67254b6ea3462db0f616ee2eba139d |
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| Source note | uspto-grants-2012_04 |
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