反应详情

To a solution of 0.36 g (1.6 mmol) of (E)-4-(hex-3-en-3-yl)-3-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one in 30 mL of ethanol was added 0.99 g (10 mol % Pd) of palladium on carbon (50% wet, Degussa type). The reaction was kept under a hydrogen atmosphere via a balloon and stirred at room temperature for 6 h. The catalyst was removed via filtration and the filtrate was concentrated in vacuo to give 0.33 g (91%) of the title compound as a grey oil that solidified upon standing.

1. customThe catalyst was removed via filtration
2. concentrationthe filtrate was concentrated in vacuo