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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1698722Generated: October 30, 2026

2-Methoxyphenylhydrazine Hydrochloride → 4-({[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]-[1-(2-methoxyphenyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]methyl}amino)benzamidine acetate

https://huagongshe.com/reaction/1698722

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxyphenylhydrazine HydrochlorideHCID 2849445—
Reactant{2-(4-Hydroxy-3,5-dimethoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene}carbamic acid methyl esterHCID 136366462—
Product4-({[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]-[1-(2-methoxyphenyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]methyl}amino)benzamidine acetateHCID 136386343—

Reaction Steps

The same procedure was carried out as in Example (6a), except that {2-(4-hydroxy-3,5-dimethoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene}carbamic acid methyl ester (Example (86a)) was used instead of the {2-(3-hydroxy-5-methoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene}carbamic acid methyl ester in Example (6a), and 2-methoxyphenylhydrazine hydrochloride was used instead of 2-hydrazinopyrimidine, to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163787B2
Source datasetuspto-grants-2012_04
ORD IDord-fa3ad7bb1cd74703a733c0da98fad57d
Source noteuspto-grants-2012_04