HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyphenylhydrazine Hydrochloride → 4-({[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]-[1-(2-methoxyphenyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]methyl}amino)benzamidine acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyphenylhydrazine Hydrochloride | HCID 2849445 | — |
| Reactant | {2-(4-Hydroxy-3,5-dimethoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene}carbamic acid methyl ester | HCID 136366462 | — |
| Product | 4-({[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]-[1-(2-methoxyphenyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]methyl}amino)benzamidine acetate | HCID 136386343 | — |
Reaction Steps
The same procedure was carried out as in Example (6a), except that {2-(4-hydroxy-3,5-dimethoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene}carbamic acid methyl ester (Example (86a)) was used instead of the {2-(3-hydroxy-5-methoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene}carbamic acid methyl ester in Example (6a), and 2-methoxyphenylhydrazine hydrochloride was used instead of 2-hydrazinopyrimidine, to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163787B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-fa3ad7bb1cd74703a733c0da98fad57d |
| Source note | uspto-grants-2012_04 |