Iodine → HCID 21118356, compound

HRID 1698754Notes

Reaction equation

HRID 1698754 reaction equation
[C:1]([CH:5]1[CH:11]([C:12]2[CH:17]=[CH:16][C:15]([Si](C)(C)C)=[CH:14][CH:13]=2)[CH2:10][C@H:9]2[N:22]([CH3:23])[C@@H:6]1[CH2:7][CH2:8]2)([O:3][CH3:4])=[O:2].[I:24]I>[B-](F)(F)(F)F.[Ag+].CO>[C:1]([CH:5]1[CH:11]([C:12]2[CH:17]=[CH:16][C:15]([I:24])=[CH:14][CH:13]=2)[CH2:10][C@H:9]2[N:22]([CH3:23])[C@@H:6]1[CH2:7][CH2:8]2)([O:3][CH3:4])=[O:2]

Participants

5

Reactant 2

HCID 807IodineHCID 131723107HCID 131723107, compound

Product 1

HCID 21118356HCID 21118356, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 159722Silver tetrafluoroborateSolvent

Procedure

This compound was synthesized by the reaction of 2-Carbomethoxy-3-(4′-trimethylsilylphenyl)tropane with I2 in the presence of AgBF4 in MeOH as a solvent at 0 C. -rt (74%).

Workup

  1. customrt (74%)

Sources & evidence

ORD record
ord-194387693a9e48b284d28164903eead8
Source dataset
uspto-grants-2002_02
Patent number
US06344179B1

Reaction notes

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