HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → (3-iodo-2-propynyl)-3N-(2-furanyl)-5-fluorouracil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Chlorouracil | HCID 15758 | — |
| Reactant | (2-Furanyl)-5-fluorouracil | HCID 324191 | — |
| Reactant | Iodopropargyl 4methylbenzenesulfonate | HCID 18321752 | — |
| Product | (3-iodo-2-propynyl)-3N-(2-furanyl)-5-fluorouracil | HCID 131723108 | — |
Reaction Steps
The procedure in Example 1 was repeated, except that 2.0477 g of 3N-(2-furanyl)-5-fluorouracil (ftorafur) (10.23 mmole) available from Aldrich Chemical Co. was used instead of 5-chlorouracil and 3.6089 g of iodopropargyl 4-methylbenzenesulfonate (10.741 mmole) and 1.060 g (7.67 mmole) of potassium carbonate were used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06344460B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-d7f4dd928e2749ac86d7ce74c00a692c |
| Source note | uspto-grants-2002_02 |