反应详情

温度

20 °C

Ex-7a) Under argon, to 65.8 g of trans-1,4-dichloro-2-butene was added in portions 47 g of potassium phthalimide with mechanical stirring maintaining the temperature between 100° C. and 110° C. The reaction mixture was then stirred for 2 h keeping the temperature between 145° C. to 150° C. It was then cooled to 20° C. and extracted with 3×400 mL of ether. The ether layer was separated and stripped to give a solid. This solid was recrystallized from ethanol to yield yellow crystals of N-(trans-4-Chloro-2-butenyl)phthalimide, wt. 36 g, 61% yield. Analysis calcd. for C12H10ClNO2 (MW 237.25): C, 61.26; H, 4.29; N, 6.02; Cl, 14.94; Found C, 61.18; H, 4.30; N, 5.98; Cl, 14.62.

1. temperaturemaintaining the temperature between 100° C. and 110° C
2. stirringThe reaction mixture was then stirred for 2 h
3. custombetween 145° C. to 150° C
4. extractionextracted with 3×400 mL of ether
5. customThe ether layer was separated
6. customto give a solid
7. customThis solid was recrystallized from ethanol