HCID 5328418, compound → HCID 5328419, compound

Participants

Reaction Steps

A solution of 4-([3-bromophenyl]amino)-6-nitrobenzothieno[3,2-d]pyrimidine (160 mg, 0.4 mmol) in methanol (10 mL) was subjected to hydrogenation with Raney Nickel (0.07 g) at 25° C. for 30 hours. After the reaction was done, the solvent was removed under reduced pressure to leave a dark brown solid. Recrystalization from wet methanol afforded 6-amino-4-([3-bromophenyl)amino)benzothieno[3,2-d]pyrimidine as a brown solid (70 mg, 43%), mp 217.6-218.8° C.

Provenance & Evidence