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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 16990Generated: October 25, 2026

1-Bromo-2-Chloroethane → 1-(2-Chloroethyl)4-(trifluoromethyl)piperidin-4-ol

https://huagongshe.com/reaction/16990

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-ChloroethaneHCID 7849—
Reactant4-(Trifluoromethyl)-4-piperidinolHCID 17951321—
Product1-(2-Chloroethyl)4-(trifluoromethyl)piperidin-4-olHCID 18449829—

Reaction Steps

A solution of 4-(trifluoromethyl)piperidin-4-ol and 1-bromo-2-chloroethane are reacted using the procedure for Example OO to afford 1-(2-chloroethyl)-4-(trifluoromethyl)piperidin-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07737283B2
Source datasetuspto-grants-2010_06
ORD IDord-be98669f9d524fc3869fd94f06b0badf
Source noteuspto-grants-2010_06